Drug-resistant epilepsy affects millions worldwide. Predicting seizures with sufficient lead time to trigger abortive electrical stimulation or warn patients requires wearable monitors that operate continuously without frequent battery recharges. This paper validates neuromorphic event-driven processors achieving 94% seizure prediction sensitivity.
Pre-ictal brain states exhibit abnormal phase-locking across distant cortical areas. Dedicated on-chip hardware calculates Hilbert transforms and phase-locking values in real time with less than 250 microwatts of power.
By requiring multiple independent frequency bands to cross coherence thresholds simultaneously, false positive alarm rates are suppressed to less than 0.08 per 24 hours.